Adipose tissue microscope video

Adipocytes are cells which contain fat globule in a single granule. They tend to fill the whole cytoplasm, thereby pushing the nucleus of the cell to the side. During tissue processing, the fat globules dissolve out of the cells and the cells now appear with holes which are characteristic and therefore diagnostic of adipose tissue and their contained adipocytes.

Differential diagnosis:  Adipose cells have holes as a result of the fat globule removed during tissue processing. Lungs have alveoli which look like holes. The difference is the septum between the alveoli in the lungs. What adipose tissues have are cell membrane and the remaining cytoplasm. But what surrounds the holes in the alveoli are alveolar epithelial cells. Other organs with multiple luminal structures such as testis and kidney have very thick intraluminal walls.

 

 
Adipose tissue microscope

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