Oviductal coculture


The realisation that the oviduct can play significant role in in vitro fertilisation and manipulations for reproductive success was first proposed by Ogunranti in 1986.  It was then suggested that coculture with oviduct cells or explants can be useful for maximising reproductive success in animal or clinical reproduction. After investigators have shown that whole explants of the oviduct can be made to output their glycoproteins in culture, it is now possible to use them for manipulating eggs and embryos for superior development. Today, co-culture with oviductal cell have improved embryo growth  and pregnancy rates at least in humans according to the data of Bongso and his associates in Singapore. 








Electronic School of Medicine
Creator: Oluwole Ogunranti