Preimplantation genetic diagnosis

In this method, small numbers of cells are obtained from in vitro fertilized eggs before implantation, sometimes at the blastocyst stage. This affords an opportunity for early detection of abnormalities that the abnormal embryos are not transferred but wasted. The technique used for identification of genes include PCR DNA based amplification and fluorescent in situ hybdridisation (FISH). The two techniques require only a few cells. The technique is now quite versatile and can detect sex of the embryo so that diseases which are linked to sex chromosomes can be detected or discriminated against (e.g. hemophilia which only affects men and make women carriers or genes linked to Y chromosome). It can also be used alone or in conjunction with sperm sifting methods to provide gender selection of family balancing. Check information from for more.























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