spleen is useful for the production antibodies against antigen present in
blood and its the only organ that performs such functions. Other organs
may produce antibodies against antigens seen or present in tissue.
produces large amounts of B and T lymphocytes through its white pulp.
the largest site for macrophage aggregations and phagocytic function in
It therefore removes old or bad blood cells and platelets.
It destroys bacteria and
foreign organisms by a process of opsonization and also phagocytosis to
include its function of producing antibodies
It stores about 33% of all
platelets in the entire body.
The open system suggests
that there is no continuity between the ellipsoids and the sinusoids.
Blood from the ellipsoids are discharged into the reticulum of
from where they are absorbed into the sinusoids.
The compromise theory
which suggests that both mechanisms take place.
make up the red pulp of the splenic pulp. They are connected to
the venules as per any of the mechanisms above and from the venules they
discharge their blood into the
splenic vein. The sinusoids are lined by
special endothelial cells which are babana shaped and contain myofibrils
that allow them to contract thereby opening up channels by which blood
is discharged into the splenic substance. They are called stave cells.
Red blood cell pass through the sinusoidal spaces. When they are old,
they are unable to pass across and they are then destroyed by the
Locator spleen video
in the red pulp of spleen. This is the theory that has the largest