Neuromuscular junction
Neuromuscular junction

Nerve which supplies muscles enters the muscle substance to the neuromuscular hilus which is usually closer to the origin of the muscle than to its insertion. The neurons which reach the muscle fibers are alpha efferents. Gamma efferents supply intrafusal fibers of the muscle spindles. The actual microscopic junction between neuron and muscle fiber is called the motor end plate.

Neuromuscular junction is just another synaptic junction but this one is between the neuron and the muscle cell, where the postsynaptic membrane is the sarcolemma and the presynaptic membrane is the neurilemma. Synaptosomes contain depolarizing agents which are neurotransmitters that pass across the synaptic cleft to reach the postsynaptic membrane that is depolarized.

 

 

 


Striated muscle explanatory video

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Central and peripheral nervous system pharmacology


 

 

 

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