Immunotherapy

 

Immunotherapy is the use of immune system to treat disease. This could be by providing antibodies which may be either monoclonal or polyclonal. A monoclonal antibody is one which is produced by only one clone of lymphocytes. It was developed by Kohler and Milstein in 1975. When a single B lymphocyte is stimulated by an antigen, to produce antibody, the resulting antibody is monoclonal but when it involves more than one B lymphocyte it builds up polyclonal. Usually in antibody production through immunization, antigen is injected into the animal body but various parts of the antigen have the capacity to stimulate antibody production leading to the development of polyclonal antibodies.

To obtain monoclonal antibody only one single lymphocyte cell (B) will be isolated and fused with a myeloma cell.


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Electronic School of Medicine
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