Histopharmacology of blood

 

Blood and plasma remain the means by which drugs interact with the body in order to  perform their functions. Blood distributes drugs to all parts of the body after absorption into the blood itself. Some affect the blood corpuscles directly.

Hemopoeitic growth factors can now be used to stimulate growth of erythroid and myeloid series of blood. Erythropoietin (epoetin) is a hormone which increases growth of erythroid series in blood. Also colony stimulating factors are available to stimulate growth of blood cells. Granuclocyte colony stimulating factors include filgrastim and lenograstim, and monocyte stimulating factor includes molgramostimThromobopoietin  is a growth factor of megakarocyte and it helps to increase population of platelets.

 

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Hemopoeitic growth factors increase red blood and other cell production with increase reticulocyte (arrow) count

 

 

 

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