Pharmacology of adrenal gland

 

Steroids drugs are all derived from structures of adrenal steroids and they include cortisone, hydrocortisone, prednisolone, methylprednisolone, dexamethasone, betamethasone, fludrocortisone and aldosterone. They are all used as steroids to treat adrenal insufficiency and to control hypersensitivity reactions and inflammation.

Epinephrine is produced in large quantities in phaeochromocytoma, a tumor of adrenal medulla. The adrenal medulla can be blocked by antagonists such as α blockers (phenoxybenzamine, doxazosin, phentolamine) and blockers (oxyprenolol, propanolol, acebutolol). α blockers are used to control vasoconstriction, while  blockers are used to control tachycardia.

Norepinephrine is used clinically to boost blood pressure in hypertension and shock. Epinephrine is used in bronchospasm.


Adrenal gland explanatory video

 

Electronic School of Medicine
Creator: Oluwole Ogunranti

      

 

 

 

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