Paget's disease of bone is caused by persistence of wooven bone in an adult. Bones are weak in this condition leading to frequent fractures. Bone fractures heals faster in children than adults.

Tumors of bones include osteoma (benign) and osteosarcoma (malignant).

Classification of bone diseases

• Diseases of bone cells, matrix and structure

  • Bone cell diseases

  • Mineral homeostasis anomalies

    • Rickets

    • Osteomalacia

    • Hyperparathyroidism

    • Renal osteodystrophy

  • Diseases of structure

    • Mucopolysaccharidoses

    • Collagen diseases

      • Type 1 Collagen disease - osteogenesis imperfecta

      • Type 2, 10 and 11 collagen diseases

    • Hormone and signal transduction errors diseases

      • Bone

      • Cartilage

    • Osteopetrosis

    • Osteoporosis

  • Fractures

  • Infections

    • Osteomyelitis

  • Tumors

    • Bone tumors

    • Cartilage tumors

    • Fibrous tumor

    • Miscellaneous tumors

      • Ewing sarcoma

      • Primitive neuroectodernal tumor (PNET)

      • Giant cell tumor

      • Metastatic tumor disease of bone

 
Osteosarcoma

Histopathology   Histology

Chondrosarcoma, differentiated
Osteogenic sarcoma of bone
Poorly differentiated osteosarcoma

Pathology      Anatomy

Chondrosarcoma of femur

 

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