Histopathology of bone

Compact bone explanatory video

Paget's disease of bone is caused by persistence of wooven bone in an adult. Bones are weak in this condition leading to frequent fractures. Bone fractures heals faster in children than adults.

Tumors of bones include osteoma (benign) and osteosarcoma (malignant).

Classification of bone diseases

  • Diseases of bone cells, matrix and structure

    • Bone cell diseases

    • Mineral homeostasis anomalies

      • Rickets

      • Osteomalacia

      • Hyperparathyroidism

      • Renal osteodystrophy

    • Diseases of structure

      • Mucopolysaccharidoses

      • Collagen diseases

        • Type 1 Collagen disease - osteogenesis imperfecta

        • Type 2, 10 and 11 collagen diseases

      • Hormone and signal transduction errors diseases

        • Bone

        • Cartilage

      • Osteopetrosis

      • Osteoporosis

    • Fractures

    • Infections

      • Osteomyelitis

    • Tumors

      • Bone tumors

      • Cartilage tumors

      • Fibrous tumor

      • Miscellaneous tumors

        • Ewing sarcoma

        • Primitive neuroectodernal tumor (PNET)

        • Giant cell tumor

        • Metastatic tumor disease of bone


  • Scoliosis
    • Postural scoliosis
    • Compensatory scoliosis
    • Structural scoliosis
  • Kyphosis
    • Angular kyphosis
    • Senile kyphosis
    • Post-traumatic kyphosis
  • Lordosis
  • Low back pain
    • Prolapsed intervertebral disc syndrome
    • Sacroiliac joint arthritis
    • Tuberculosis of sacroiliac joint
    • Lumbosacral strain
    • Low back pain without physical signs
      • Malingerer
    • Pott's disease
    • Non tuberculous spondylitis
    • Ankylosing spondylitis
    • Spondylisthesis
    • Fractures of spine




Histopathology   Histology

Chondrosarcoma, differentiated
Osteogenic sarcoma of bone
Poorly differentiated osteosarcoma

Pathology      Anatomy

Chondrosarcoma of femur

Bone microscope video































Cell biology
Gross anatomy
Organ integration
Clinical anatomy





Chemical Pathology

Anatomical Pathology





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