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Disseminated intravascular coagulopathy

This is a complication of antepartum hemorrhage which has been long standing. It is a result of the depletion of blood clotting factors as a result of chronic blood loss. It is best treated with replacement of blood with fresh blood and clotting factors to include fibrinogen.

Factors which may be deficient in this syndrome include fibrinogen, factor II, V, VIII and X. Caesarean section is indicated and must be performed immediately to remove the baby.

Other treatment in addition to fresh whole blood and fibrinogen may include

  • Packed red cells
  • Cryoprecipitate packs
  • Platele transfusion
  • Heparin
  • Fibronolysins.






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