Receptor

 

GastrinA protein group or other molecule which is found in the cell surface of a particular cell type or sometimes in the interior of the cell which is capable of interacting with a molecule that forms its 'mirror image' or chemical designation or for which it is has chemical affinity. This affinity and binding to the receptor site and chemical agent leads to a cascade of chemical reaction causing some physiological effects. These receptors also have affinity for substances that do not cause the physiological effect mentioned and the the reaction effected may then be inert. The later group are referred to as blockers as opposed to the substances that cause effect which are then called agonists.

The prinThe receptor principle is used extensively in pharmacology where drugs can cause effects (agonists) or non effects (antagonists) especially in the nervous system. Hence you have adrenergic receptor or cholinergic receptors in the central nervous system etc. The chemical receptor must be distinguished from neural biological receptor which receives neural impulses.

 

 

cAMP

Adenylate cyclase system

Intracellular receptors

Calcium messenger system

 

 

 

 


Central and peripheral nervous system pharmacology 

 

 

 

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