White blood cell



White blood cells  (granulocytes) are about 10 μm in diameter and are therefore larger than red blood cells.  They are phagocytic cells and are responsible for fighting infection and engulfing foreign bodies found in the blood.  They are amoeboid in movement.  They usually number about 4-11 thousand/cubic millimeter (/ul) but they can increase in conditions known as leucocytosis to about 25,000 /cubic millimeter (/ul) or above

They increase in such conditions as bacterial (pyogenic) infections and also in conditions of stress, emotional strain and exercise.  In certain conditions, as in disease, they reduce in number (leucopenia). Cholesterol increases the absolute number of leucocytes with predominant neutrophilia in blood stream followed by lymphopenia while the lack of cholesterol in diet has the opposite effect with reduction in neutrophil (physiological or diet neutropenia) and absolute number of white cells, but increase in lymphocyte (lymphocytosis) in blood stream. The movements occur into and away from tissue deposits by diapedisis.

White blood cells are as follows

Polymorphonuclear leucocytes/granuclocytes

















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Electronic School of Medicine
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Effect of cholesterol in diet on mobilization of leucocytes in tissue stores animated. It causes mobilization from tissues and increase in circulating leucocytes, mainly neutrophils

Effect of cholesterol in diet on mobilization of lymphocytes in tissue stores. It causes deposition in tissue and reduction in circulating lymphocytes




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