Stomach

Stomach Chart

Cell types: Mucous epithelial, mucous gastric gland neck, chief, parietal, pyloric gland, enteroendocrine cells.

Differential diagnosis:
Other columnar epithelium of the rest of the gut tube can be distinguished from the stomach by the absence of gastric pits or tall glands which are narrow. Rectal and colonic glands (crypts) are tall but not narrow.

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Diagnostic Features:
a. Tissue is hollow and presents with a large lumen which fills more than 1/10th of low power field.
b. There are no villi but rugae which resemble villi. The surface epithelium is provided with gastric pits which are characteristic.
c. Simple columnar epithelium covers the surface and there are no glands in the submucosa. But gastric glands on the epithelium are tall and very narrow.
d. The muscularis is provided with inner oblique, circular and longitudinal muscles.

Draw your own section here and make your diagnosis by data base selection below

Database selection:

Practical

Tissue

Gross

Level 1: Select hollow since the stomach is a hollow organ
Level 2: Select large as opposed to small since lumen fills more than 1/10th of low power field for tissues of rat to man. This will select form database both cartilage and non cartilage containing tubes.
Level 3: Select no cartilage. This eliminates the trachea and other respiratory tract tubes and selects mainly digestive system organs.
Level 4: Select digestive system
Level 5: Select villi which picks up all structure in the gut which presents with villi or villi-like structures and they include duodenum, ileum and jejunum. With pits (villi pits) it eliminates other structures and selects stomach.

Note the musculature of the muscularis externa. Can you identify the oblique innermost layer? Compare TS and LS; can you note the differences in the height of glands in fundus, pylorus and cardiac regions?