Small bronchus                                   Chart

                            
Cell types: Ciliated, brush, basal, goblet cells
 

Differential diagnosis:
 All small hollow organs (non-respiratory and respiratory) are distinguished on the basis of availability of distinct outer coats. The respiratory tubes have no distinct coat since they merge with lung tissue. Appendix or oviduct do have distinct coats and should therefore not be confused with respiratory small luminal organs. Bronchus can be distuinguished from bronchioles by the presence of submucous glands, goblets cells and also pseudostratified epithelium in the bronchus.

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Diagnostic Features:
a. Tissue is hollow and presents with a small lumen which fills less than 1/10th of low power field.
b. The epithelium is of pseudostratified variety and there is minimal cartilage of hyaline variety.
c. There is muscular tissue also in adventitia and some submucous glands but no distinct outer coat. Lung tissues or alveoli are present in abundance.
d. Goblet cells are few.

Draw your own section here and make your diagnosis by data base selection below

 

 

 

 

 

 

 

 

 

 

 

Database selection: Practical Tissue Gross

Level 1: Select  hollow since the small bronchus is a hollow organ
Level 2: Select small as opposed to large since lumen fills less than 1/10th of low power field for tissues of rat to man. This will select from database both cartilage and non cartilage containing tubes.
Level 3: Select no distinct outer coat since the coat merges with surrounding lung tissue.
Level 4: Select cartilage which is found in adventitia. This eliminates non respiratory organs such as appendix which do not have cartilage. The availability of goblets cells, pseudostratified epithelium and glands distinguishes it from bronchioles.

Note the musculature of the adventitia and its cartilage.

 

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