D cell

 

  

 

These are argyrophilic pancreatic endocrine cells which are also APUD cells. They are pyramidal in shape and they are mainly open type cells with their apical end possessing medium-sized microvilli. The granules are about 300-400 microns in diameter and are characteristically round. They are thought to produce somatostatin. Amine products have not been identified.

D cell of the pancreatic islet which form 10% of islet cell population. It increases in number in diabetes mellitus and it has uniformly round granules which are larger than those for A and B cells.  It has been shown that the D cell produce somatostatin. It may also produce gastrin.

 

 

 

 

 

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