A cell

 

  

 

A-cells are APUD, entero endocrine cells and they form about 20% of islet cell population in the human pancreas. It is recognized by the characteristic double structured membrane of its granule. The granules are about the same size  as in B-cells. They contain an electron dense cortex with a halo underneath the membrane.  These cells produce glycagon which was proven conclusively by immunofluorescent studies. B and A cells are closed type endocrine cells, but they are thought to possess microvilli which help to ‘taste’ blood and determine the level of blood sugar in order to respond to it.

 


 

 

 

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