H/E x40
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X200
Differential diagnosis: Click to demonstrate

Esophagus                                                                              Skin

The tongue has similar stratified squamous epithelium as the skin. It also has projecting papillae at its surface. Its external layer is the muscular layer, which is striated.

The tongue can be confused with skin and esophagus because of the common epithelium, but the skin can be distinguished by the subcutaneous fat and esophagus by its esophageal glands in its submucosa.

Ultrastructure
Histology
Embryology
Gross anatomy