The lymph node is the center of lymphocytic activity and hence has many lymphocytes. Its appearance in hematoxylin-eosin stain is therefore bluish in color. It is made up of a peripheral cortex and a central medulla. The cortex contains many lymphatic nodules whose centers are light staining, containing the germinal  centers for the proliferation of lymphocytes

Differential diagnosis: Lymph nodes can be easily confused with the spleen, thymus and tonsil All are lymphatic organs and they have lymphocytes in abundance. Examine their features, which aid their recognition.

Ultrastructure
Histology
Embryology
Gross anatomy