Adrenal gland


Germ layers  [Interactive video text]

Neural crest cells are budded off from the upper margins of the tube. They are very migratory and they move downwards to form many structures. They form many cell groups such as the sympathetic ganglia which later form the medulla of the adrenal gland. The cortex of the adrenal gland differentiates from surrounding mesoderm, while the medulla, just like the nervous tissue, comes from the ectoderm. The adrenal corex is first noticed at the 6th week of gestation  by aggregation of mesenchymal cells one each side  and close to the developing gonad. It is derived from the mesothelial lining of the posterior abdominal wall while the medulla is derived from adjacent sympathetic ganglion which is also a derivative of the neural crest. At the later fetal stage, zones are formed in the cortex as the following

  • Zona glomerulosa

  • Zona fasciculata

  • Zona reticularis.

 

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